Pericentriolar Targeting of the Mouse Mammary Tumor Virus GAG Protein.
The Gag protein of the mouse mammary tumor virus (MMTV) is the chief determinant of Gift subcellular targeting.Electron microscopy studies show that MMTV Gag forms capsids within the cytoplasm and assembles as immature particles with MMTV RNA and the Y box binding protein-1, required for centrosome maturation.Other betaretroviruses, such as Mason-c